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Hand-Foot Syndrome (HFS) Hand-foot syndrome (HFS) is a reaction of the skin to certain chemotherapy agents, including 5-FU, capecitabine, cytarabine (Depocyt), and pegylated liposomal doxorubicin (Doxil, Caelyx)

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Its activity is studied through copper transport and signaling interactions rather than one receptor

Likewise, dietary supplementation with GSH improves the growth, anti-oxidative capacity, disease resistance and gut morphology in juvenile Atlantic salmon [33], common carp [47], triploid rainbow trout [48], shrimp [49], and crabs [50]

10,12 Considering that AP2 is expressed in PGCs from E7.5 to E12.5, a period encompassing the entire germ cell migration period, our work supports the notion that AP2 is not only important for PGC specification but also critical for the maintenance of germ cell fate in migrating PGCs