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The combination group showed larger changes in body weight and whole-body adiposity than the diet-change-only group during the experimental period

Study design Randomised controlled trial (RCT)

Although the use of glucagon alone may not be favorable for weight management, combining it with other gut-pancreatic hormones (such as GLP-1) might represent a new direction in the development of drugs for obesity, aiming to balance blood sugar regulation with weight reduction