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Discussion In this phase 2, randomized, double-blind, placebo-controlled trial of orforglipron, participants in all dose cohorts (12, 24, 36, and 45 mg) had a greater decrease from baseline in body weight than those in the placebo group, both at 26 weeks (primary end point) and at 36 weeks (secondary end point)
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Similar to Ozempic in their mode of action, these drugs may have slightly different dosing or administration guidelines
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