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The most common infections are of the upper respiratory tract

58 Phase 2a trial of GSBR-1290 (120mg) in 40 healthy obese volunteers over 8 weeks demonstrated a significant reduction in BW (120 mg: -4.74%

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) were initially developed for glycaemic control in type 2 diabetes and some have also demonstrated efficacy in weight reduction and cardiovascular risk modification in non-diabetic populations

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For constipation management , increasing dietary fiber intake through fruits, vegetables, whole grains, and fiber supplements (such as psyllium) can promote regular bowel movements