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Some users have reported delays and challenges during periods of high demand, but overall feedback is positive regarding value and simplicity

They achieve sustained acid suppression for more than 12 h, which is over twice the duration of action of traditional PPIs, with a 3.2-fold increase in local drug concentration

Importantly, prescribing must still meet licensed indications and NICE/local commissioning criteria

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In addition to short-term symptoms like headache, nausea and anxiety, concussions can also cause long-term effects, such as cognitive impairment and depression