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In the mouse model of STZ-induced DKD, proximal tubule-specific knockout of Atg5 aggravates tubule injury and kidney damage, reflected as defective autophagy sensitized proximal TECs to ferroptosis (79)

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Taking into account the selective, dynamic and adaptive aspects of the bloodbrain interfaces together with inspiration from the domain of political philosophy [8], we believe that the notion of a border, rather than that of a barrier, better captures the properties of these interfaces