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Stimulates burning, among others, in the area of adipose tissue and skeletal muscles

But research has documented that retatrutides glucagon receptor activity produces useful metabolic effects (increased energy expenditure, fatty acid oxidation) without compromising the glucose-lowering effects of the GLP-1 component

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These conflicting findings are challenging to interpret and may be related to many factors, including different animal models, different effects of reagents, or genetic interventions on inflammation