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Clinical studies confirm that up to 500 mg daily is safe for up to 2 months

They have less appetite

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doi: 10.1172/JCI116186 89 VilsbllTKrarupTMadsbadSHolstJ

As the feasibility of large-scale production, for example, the size and shape, ratios of the weight and volume to the reaction volume, and stirring conditions employed in this study would be reproducible when increasing the reaction volume to 1,000 mL for repeated batch reactions of NsPCS immobilized on both the cellulose sponge and MCC