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As a pivotal study for the oral form, this study had a shorter duration (16 months) than the other studies (2-5.4 years) [5,712]
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In addition to its direct antioxidant functions, glutathione (GSH) contributes to the regeneration of other antioxidants, including vitamins C and E, and is involved in critical processes such as iron homeostasis and mitochondrial integrity
Based on previous studies and a review of relevant literature, we hypothesized that SIRT1 is a promising target for GHK-Cu in UC treatment, which will be verified in the subsequent experiments
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