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IGF-I deficiency is associated with growth hormone insensitivity syndrome (GHIS) also called Laron syndrome, liver cirrhosis, age-related cardiovascular and neurological diseases, and intrauterine growth restriction

Copper peptides enhance collagen production, which strengthens the hair shaft, improves elasticity, and reduces hair breakage

people at higher risk of deficiency include older adults, those with gastrointestinal issues that impair absorption, people whove had gastric surgery, long-term strict vegans who do not supplement, and those on certain acid-reducing medicines

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A neurosurgical piston with a graduated force of 6066 g was placed over the exposed dura and left for 60 s to induce a compression injury