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Preclinical studies in rodents have demonstrated reductions in fat mass, improved insulin sensitivity, and increased metabolic rate without significant changes to food intake (Neelakantan et al., 2019)
Evidence comparison: GHK-Cu has a substantially larger body of published research, spanning from Pickart's original 1973 isolation through hundreds of subsequent studies
SS-31 targets mitochondrial function directly
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Effect on the gut microbiome: Studies in mouse models show that 5-Amino-1MQ, when combined with diet, affects the gut microbiome, which may have long-term metabolic effects
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