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Recent experimental studies demonstrate that stabilizing mast cells with cromolyn after ischemic stroke reduces peripheral and central inflammation, preserves gut barrier integrity, mitigates dysbiosis, and improves functional outcomes, underscoring the pivotal role of gut-derived mast cells and histamine in post-stroke neuroinflammation (Conesa et al., 2023)

Gao, X., Liang, H., Hou, F., Zhang, Z., Nuo, M., Guo, X., & Liu, D

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