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Herein, an increase in xanthine levels and a decrease in XDH expression in cells under continuous tamoxifen treatment was noted indicating a switch from xanthine oxidation to the purine salvage pathway and thus increased purine nucleoside synthesis
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10.1054/mehy.1998.0780 Shungu, D.C., N
It contaminates your entire data set, wastes your time, and erodes the foundation of your study
Notably, a similar phenomenon was observed in neurons from patients with MS, characterized by upregulated STING expression and markedly reduced STIM1 expression, suggesting that STIM1-STING-GPX4 axis-mediated ferroptosis is closely associated with neuronal injury in human MS pathology (Woo et al., 2024)
