The starting dose is 2.5 mg per week
Kossman, D
429,430 Although testosterone levels were not significantly different in men with combat-related post-traumatic stress disorder (PTSD, a chronic stress-related ailment) than in healthy controls, 431 they were higher in those with PTSD that was not complicated by major depression or alcoholism
Biochem Biophys Res Commun 505(2):523529 Daniels SJ, Leeming DJ, Detlefsen S, Bruun MF, Hjuler ST, Henriksen K, Hein P, Karsdal MA, Brockbank S, Cruwys S (2019) Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-) agonist and a glucagon-like peptide-1 analogue
One 2022 review of studies in Frontiers in Nutrition on berberine supplementation for adults with cardiovascular disease risk found that supplementing it reduced weight and body mass index (BMI), as well as other metrics like cholesterol and blood pressure