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Future: Dedicated NASH Phase 3 Trial - NOT YET STARTED Status: Expected 2027-2030 (after obesity/diabetes approval) What This Would Include: Liver biopsy as PRIMARY endpoint NASH resolution as primary outcome Fibrosis improvement measurement Required for FDA approval specifically for NASH indication Why Wait

The findings published in The Lancet Diabetes & Endocrinology , along with results from a related clinical trial published concurrently, suggest that patients seeking to lose more weight can safely take a higher semaglutide dose than typically prescribed

R., Radwan, P., Radwan, M., Barcz, E., Poski, R., Motak-Pochrzst, H., Banasik, M., Sobczyski, M., & Kunierczyk, P

Mild and temporary side effects may include localized injection site irritation, transient water retention, or changes in appetite