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The washout allows tirzepatide levels (half-life 5 days) to drop substantially before adding a new triple agonist

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Based on prior literature, biotin-hydrazide could detect the allysine products and Schiff base-type proteinprotein crosslinks derived thereof on extracellular matrix proteins 38 and potentially react with the carbonyl group on the LTQ, inhibiting LOX activity 33,51

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