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Unger RH (1973) Radioimmunoassay of glucagon

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The tripeptide upregulates collagen I and III synthesis, stimulates angiogenesis via VEGF pathways, and modulates the NF-kB inflammatory cascade toward resolution rather than amplification

demonstrated that GLP-1 RAs could alleviate cytoplasmic Ca 2+ overload in VSMCs in SHRs, improve the arterioles systolic and diastolic functions, and reduce BPV by upregulating Na + /Ca 2+ exchanger 1 (NCX1) expression via the Akt signaling pathway [80]

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