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Neuropsychopharmacology 37:338349 Summer GJ, Romero-Sandoval EA, Bogen O, Dina OA, Khasar SG, Levine JD (2008) Proinflammatory cytokines mediating burn-injury pain

Toxicology research indicates the peptide has no lethal dose in rat models even at extremely high concentrations, and chronic administration studies show no organ toxicity or significant biochemical abnormalities