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J Physiol Paris 91:113122 Keremi B, Lohinai Z, Komora P, Duhaj S, Borsi K, Jobbagy-Ovari G, Kallo K, Szekely AD, Fazekas A, Dobo-Nagy C et al (2009) Antiinflammatory effect of BPC 157 on experimental periodontitis in rats

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doi: 10.1371/journal.pone.0099835 129 ZhouGXLiXYZhangQZhaoKZhangCPXueCHet al

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Thus, Scd1/2 (stearoyl CoA desaturase-1/2), and Ptgis (prostaglandin I2 synthase) located in the endoplasmic reticulum, belong to the unsaturated fatty acid biosynthetic process pathway catalyzing reactions involved in the synthesis of cholesterol, steroids, and other lipids 35