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Compared with untreated individuals, those receiving GLP-1 therapy showed lower levels of pro-inflammatory cytokines (IL-6, TNF-, IL-12), higher levels of IL-10, reduced expression of endothelial adhesion molecules (ICAM-1, VCAM-1), and decreased leukocyte rolling and adhesion along the vascular endothelium [15]

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This step-by-step approach, called dose titration, helps make treatment easier to tolerate while still allowing the medication to work effectively

(PubMed) Lenzi A, Lombardo F, Sgro P, et al

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