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These studies demonstrated statistically significant improvements in sexual desire as measured by the FSFI-Desire score, reduced distress associated with low desire on the FSDS-DAO scale, and sustained effects observed over 24 weeks of treatment

Evidence from the SURPASS phase III clinical trial program has consistently demonstrated the superior metabolic efficacy of tirzepatide compared with currently available GLP-1 receptor agonists, such as semaglutide

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Insulin secretagogues (sulfonylureas and meglitinides) should be discontinued to reduce the risk of hypoglycemia [Grade D, Consensus]