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107,108 In ME2-unexpressed gastric cancer cells, its isoenzyme ME1 is upregulated to replenish intracellular NADPH and promotes cell survival under glucose starvation and anoikis

A major open question at this point is how the spending impact of these drugs might compare to the avoided cost of alternative treatments

Presented in a 3 mL pre-filled precision pen system

Synthesized via SPPS and purified to analytical standards by HPLC