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demonstrated that, relative to the ad libitum group, the CR group showed markedly higher levels of bone resorption markers (CTX and TRAP5b), accompanied by a notable decrease in the bone formation marker bone-specific alkaline phosphatase (BAP)

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Furthermore, users of tirzepatide reported an average waist size reduction of 7 inches, alongside improvements in blood pressure, blood sugar, and blood fat levels, further underscoring its effectiveness

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Studies were categorized according to the duration of therapy, with the majority reporting outcomes after a 6-month follow-up period