Neuroanatomy of the Human Hypothalamic Kisspeptin System
98 Although located in the sinoatrial node, GLP-1 RAs influence the cardiovascular system through several other mechanisms, including the use of myocardial glucose, improvement of left ventricular function, myocardial ischaemic protection, increased heart rate, vasodilation, anti-atherosclerotic effects, and blood pressure reduction
Electrolyte imbalance can also trigger headaches
Lixisenatide: Gastrointestinal: acute pancreatitis, hemorrhagic and necrotizing pancreatitis, ileus, intestinal obstruction, severe constipation including fecal impaction Hepatobiliary: cholecystitis, cholelithiasis requiring cholecystectomy Neurologic: dysgeusia, dysesthesia Pulmonary: pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists under-going elective surgeries or procedures requiring general anesthesia or deep sedation
it must involve nurturing the internal environment of the gut