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As the pharmacological action and impact on CV parameters interpreted from the CV outcomes trials seemingly differed between both classes of glucose-lowering agents, they should be used accordingly, that is, after taking into consideration a patients needs and drug tolerability

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Under non-stressed GSH concentrations, GSH-conjugation of AQ-QI and DEAQ-QI was twofold higher in GSTP1 -transfected cells ( Figure 5A )