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Figure 3 In conclusion, SLC7A11 has a pro-survival effect, and SLC7A11-mediated cystine uptake can help cells re-establish redox homeostasis in response to oxidative stress, whereas inhibition of SLC7A11 can lead to depletion of cellular GSH and thus make the cells more sensitive to chemotherapy or radiotherapy
Thirdly, glutathione boosts the immune system by activating T-lymphocytes and leukocytes that are part of the immune response of the body, thus ensuring a competent immune system facing any health hazards oxidative stress can cause (3)
This establishes a chronic inflammation-oxidative stress vicious cycle
doi: 10.1155/2019/9372182 232 RodriguesP
It can also raise inflammation and lower a protein involved in controlling the amount of estrogen and testosterone actively present in the body
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