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This reassignment was to ensure that the colors in the heatmap were balanced
Berberine inhibits neuronal apoptosis by regulating autophagy-related proteins [Microtubule-associated protein 1A/1B-light chain 3 (LC3), Beclin-1, p62], and apoptosis regulatory proteins [caspase 3, caspase 8, caspase 9, poly ADP-ribose polymerase (PARP), and B-cell lymphoma 2 (Bcl-2)/Bcl-2 associated X (Bax)] (Zhang et al., 2016)
Patients who are using skin lightening products or undergoing other skin lightening treatments should refrain from exposing themselves as best they can throughout the duration of treatment to avoid risking skin damage, including skin cancer
Patients who are pregnant, breastfeeding, or managing a health condition should review the product with a provider first
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