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Nakazawa H, English D, Randell PL, Nakazawa K, Martel N, Armstrong BK, et al
In the laboratory it is typically supplied as a lyophilised (freeze-dried) acetate salt that is reconstituted before use
When bone density goes down, the skeleton isn't as strong
However, successful clinical translation will require addressing persistent challenges, including biosafety, biodistribution, tumor heterogeneity, and large-scale manufacturability
doi:10.1016/S0140-6736(23)01163-7 Davies MJ, Bajaj HS, Broholm C, et al
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