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From the preclinical data for putative benefits there were also important side effects noted

A controlled, randomized, double blind study (author's transl)]

The researchers hypothesized that weight loss with AOD9604 was driven by the beta-adrenergic pathway, more specifically the beta(3)-adrenergic receptors

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[6] The core AOD9604 studies do not provide a validated comprehensive gene-expression signature covering HSL, ATGL, CPT1, MCAD, PGC-1alpha, UCP1, leptin, and adiponectin