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The significant increase in the number of overweight people observed in recent decades therefore essentially reflects the overconsumption of food, possibly due to the omnipresence of industrial foods that are extremely attractive because of their organoleptic properties (palatability) and which lead to excessive energy intake

The lack of transparency means we still dont have vetted safety data from a controlled trial

This Review is supported by the US National Institute on Alcohol Abuse and Alcoholism (NIAAA) of the National Institutes of Health (NIH-NIAAA RO1 AA016848, NIAAA R37 AA016848, NIH-NIAAAP50 AA017072, R01AA014366 and U01AA023489) to D.R

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