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Natalie Telis, PhD

Of note, a small number of cases of acute pancreatitis associated with GLP-1RA use have been reported in clinical trials: 38 cases in 17,775 patient-years of exposure compared with 9 events in 5863 patient-years of exposure with the comparator treatment

The 56-week COR-I trial studied the use of Contrave in patients with a BMI of 27 or higher and found that participants taking a combination of naltrexone and bupropion lost an average of 4.8% more weight than those given a placebo

Retatrutide is a synthetic peptide drug designed to mimic and activate three natural hormone receptors: GLP-1, GIP, and glucagon

a High-quality evidence from consistent RCTs or meta-analyses