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Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats

The drug or matching placebo were given for 12 months and the primary endpoint, as shown below, was a motor score used by neurologists (Movement Disorder Scale-Unified Parkinsons Disease Rating Scale) MDS-UPDRS Part III)

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Conversely, the combination of GLP-1 M with thiazolidinediones was associated with a decreased response (Table 5), while sulfonylurea use showed no significant effect