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These biological actions define the counter-balancing catabolic role that glucagon serves relative to insulins anabolic action

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Copper toxicity, oxidative stress, and antioxidant nutrients

Common side effects are usually minor and related to the IV insertion itself

Therefore, we hypothesize that deregulated homocysteine metabolism in homocystinuria with severe hyperhomocysteinemia will lead to the cyclization of homocysteine into homocysteine thiolactone, which may render LDL less susceptible to oxidation