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Animal experiments have shown that mice inoculated with lung cancer A549 cells treated with IGF-1 LR3 (0.2 mg/kg/d) showed a 2-fold increase in the number of lung metastatic nodules and a 30% reduction in survival time
Mitochondrial dysfunction, nutrient depletion, hormone imbalance, chronic stress, infections, and inflammation can all contribute
It cites one small uncontrolled study suggesting modest additional weight loss, then notes that its size and design limit how far the finding can be generalized
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Its easy to think that by taking less, you can get at least some of the benefits without reaching a threshold that includes any drawbacks
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