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EMBO Mol Med 15:EMMM202217052-

Endocrinology (2008) 149(6):316775

Notably, mitochondrial autophagy downregulates mtROS levels by clearing damaged mitochondria, while deacetylases such as SIRT3 inhibit this pathway by enhancing antioxidant enzyme activity

Sequential accumulation of driver pathway mutations induces the upregulation of hydrogen-sulfide-producing enzymes in human colonic epithelial cell organoids