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Retrospective analysis of OA progress in type 2 diabetes patients showed the lower ratio of knee arthroplasty in patients treated with metformin, suggesting the possibility of clinical effectiveness
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cell transformation, genome instability, hyperproliferation, immortalization, angiogenesis, epithelial-mesenchymal transition (EMT) and metastasis, which are all influenced in several ways by intracellular ROS 48,49
Collaboration, N
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