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Firmicutes , from which Ruminococcus and Megasphaera were the top two genera of discriminant abundance, and a decreased abundance of the phylum Bacteroidetes was observed in psoriasis patients, which might be associated with suppressed cobalamin and iron transport

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Vitamin A is also important to the normal function of several types of immune cells important in the innate response, including natural killer (NK) cells, macrophages, and neutrophils

Therefore, a deficiency in L-Glutamine not only starves the gut and immune cells but also severely cripples the body's primary defense mechanism against systemic oxidative damage, creating a vicious cycle of cellular injury and fatigue