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The important caveat is that most robust clinical evidence for these medications - including the trials underpinning their UK regulatory approval - is based on longer-term use, typically 68 weeks or more

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Trial data consistently show the combination arms exceeding cagrilintide-alone arms 15.6% vs 8.1% at 32 weeks in the Phase 2 diabetes trial (Frias et al., 2023), and a 22.7% combination figure at 68 weeks in REDEFINE 1 (Aronne et al., 2025)

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The FDA determined that the semaglutide shortage was resolved on February 21, 2025

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Government and Private Funding Government and private funding play a crucial role in driving the growth of the market by providing the financial resources needed to support large-scale, long-term studies

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