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References [Alaxknits]
Synthetic insulin, for example, has been used for decades to manage diabetes, dramatically improving many lives
Diabetes Prevention Notably, in SURMOUNT-1, tirzepatide reduced the progression from prediabetes to type 2 diabetes by 94% compared to placebo, suggesting strong preventive potential
For example, INS , islet amyloid polypeptide ( IAPP ), MAF bZIP transcription factor A ( MAFA ), pancreatic and duodenal homeobox 1 ( PDX1 ), and NK6 homeobox 1 ( NKX6.1 ), exhibited a varying degree of expression in cell subclusters, with the highest expression in -4 cells (Figure 3D)
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