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Avoid vigorous exercise within an hour of bedtime, though, as this can keep you up

Participants returned to their usual insulin for a washout period of 2 weeks

When combined with the metabolic changes that happen while taking GLP-1 medications, the result can be greater fatigue. Scientific American notes that the only way to prevent muscle loss somewhat while losing weight is to combine exercise (particularly resistance exercise and endurance exercise) with a diet higher in protein

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