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Despite this rapid clearance, SFN and its conjugates effectively distribute to various tissues, including the prostate, lung, and bladder, where they can accumulate at concentrations sufficient to exert biological effects, as demonstrated in both rodent models and human tissue biopsies (47, 48)
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(2) Patients with major heart, liver, kidney, and other organ disorders, including co-infection with hepatitis C virus (HCV), hepatitis D virus (HDV), or other chronic liver diseases such as alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), and autoimmune hepatitis
Retinoids can increase skin sensitivity, and vitamin C is acidic enough to compromise the stability of copper peptides if used together
