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For upcoming studies, it would be important to identify any potential high-risk subgroups as well as assess whether the elevated risk of NAION is a drug class effect or a specific finding for subcutaneously administered semaglutide. 12.02.24 MDL cases continued to grow in December The GLP-1 MDL continued to grow, bringing the total number of cases in the docket to 1,300
However, these results require confirmation in randomized controlled trials
and (v) differences in blinding and reporting standards
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Oxidation can still occur if the vial isn't properly sealed (oxygen exposure oxidises the copper ion), but the rate is negligible in vacuum-sealed or nitrogen-purged vials
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