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It mimics a natural hormone in the body called GLP-1 (glucagon-like peptide-1), which helps regulate hunger and blood sugar
This shift is potentially advantageous for endurance athletes, as it suggests a preservation of muscle glycogen stores during exercise
While other GLP-1RAs have shown to cross the blood-brain barrier [16], SEM has been found to interact with the brain primarily through the circumventricular organs (CVO) and brain regions adjacent to the CVO [17, 18]
It plays a vital role in transporting fatty acids to the mitochondria, which are broken down to produce ATPthe primary energy source for muscle function
heterogeneity for CANVAS versus the other 12 CVOTs, p = 0.0007) [76]
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