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Oxidative stress and neuroinflammation create a reciprocal pathological process that facilitates redox imbalance and contributes to immune dysregulation in the central nervous system (CNS)

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Age-related diseases are related to structural changes in mitochondria, accompanied by the alterations of biophysical properties of the membrane including alteration in the electron transport chain complexes activities, decreased fluidity, and subsequently resulted in energy imbalance and mitochondrial failure

Superoxide dismutase acts as an important antioxidant and requires copper as a cofactor