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The trial investigated Retatrutide as an agonist of the GIP, GLP-1 and glucagon receptors
Weight loss effects comparable to prescription GLP-1 medications are not substantiated by supplement research
GIP also enhances insulin secretion and may influence fat metabolism
(27) Using data from the Clinical Practice Research Datalink Aurum, a propensity score-matched retrospective cohort study involving 25,422 participants with type 2 diabetes was conducted to compare the outcomes of patients who initiated GLP-1s vs
FDA-approved GLP-1 drugs like Wegovy are explicitly cleared for weight loss in people with a BMI over 30 and for those with a BMI below 27 who have weight-related comorbidities like diabetes, hypertension, high cholesterol, and sleep apnea
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