Weight loss is the most visible change, with clinical trials demonstrating average reductions that vary by medication: approximately 5-10% with liraglutide (Saxenda), 15-17% with semaglutide 2.4mg (Wegovy) in the STEP trials, and up to 20% with higher doses of tirzepatide in the SURMOUNT programme
The Negatives: What the Trials Showed Across programs like STEP, SURMOUNT, and SELECT, side effects were largely gastrointestinal: Nausea, vomiting, constipation, diarrhea
With regular monthly sessions, many clients find their skin holds improvements longer between appointments
Anyone with a personal or family history of medullary thyroid carcinoma or MEN 2 (boxed warning), and it should be avoided in pregnancy
However, your body has become resistant to insulins effects