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Of the 1,715 adult epileptic patients treated with topiramate at doses of 200 to 1,600 mg/day, 28% discontinued treatment because of adverse reactions which included sleepiness (3.2%), feeling dizzy (2.6%), balance issues (2.2%), paresthesia (2%), and language problems (2%)

Adequate B12 is also important, as deficiencies of B12 have been shown to reduce glutathione [54]

cholelithiasis (RR = 1.9

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