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GLP-1 receptors are expressed in the enteric nervous system and in the vagus nerve (Grasset et al., 2017), which allow for the activation of the gut-brain-periphery axis
Clinical data shows that weight loss plateaus if medication is discontinued, returning to baseline within 12 months
Why it matters for body composition: GH plays a crucial role in lipolysis (fat breakdown) and muscle protein synthesis
If future studies continue to confirm its benefits, retatrutide could emerge as one of the most powerful treatment options yet for people living with type 2 diabetes and obesity
Follow-up visit fees: Ongoing medical supervision may require periodic follow-up visits, each potentially carrying a fee
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