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[25] Murine cells overexpressing the NADase CD38 consumed less oxygen, had higher lactate levels, and had abnormal mitochondria, including traits like missing or enlarged cristae, which lends more proof of NAD+s role in promoting mitochondrial and metabolic health

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Nausea is the most common side effect and is usually manageable with dietary adjustments such as eating smaller meals, avoiding high-fat foods, and eating slowly