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The expiration of a patent is in the public domain: anyone is legally free to use, make, sell, or improve upon the previously protected invention without obtaining permission or paying licensing fees

Sustained weight loss is better than rapid weight loss Although rapid weight loss can be appealing, losing weight too quickly can increase the risk of fatigue, nutrient deficiencies, muscle loss, and rebound weight gain

Patients who see dramatic drops in their hemoglobin A1c within weeks face higher risk than those whose diabetes control improves slowly over months

Studies have revealed that alpha lipoic acid can help reduce the appearance of wrinkles and age spots when taken orally

Constipation or diarrhea may also appear